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Universitätsklinik für Psychiatrie und Psychotherapie

Labor für Psychophysiologie und funktionelle Bildgebung

 PD Dr. M.J. Herrmann

 

Füchsleinstr. 15
97080 Würzburg
Tel.: 0931 / 201-76650
Fax.: 0931 / 201-77550

1. Grundlagenforschung

1.a Handlungskontrolle

Koordinator: Stefanie Biehl

Fragestellung: Interferenzkontrolle bei Arbeitsgedächtnisprozessen

Schreppel, T., Egetemeir, J., Schecklmann, M., Plichta, M. M., Pauli, P., Ellgring, H., Fallgatter, A. J., & Herrmann, M. J. (2008). Activation of the prefrontal cortex in working memory and interference resolution processes assessed with near-infrared spectroscopy. Neuropsychobiology, 57(4), 188-193.

Schreppel, T. J., Pauli, P., Ellgring, H., Fallgatter, A. J., & Herrmann, M. J. (2008). The impact of prefrontal cortex for selective attention in a visual working memory task. Int J Neurosci, 118(12), 1673-1688.

 

1.b Emotionsverarbeitung und Emotionsregulation

Koordinator: PD Dr. M.J. Herrmann
Fragestellung: Neurophysiologische Korrelate emotionaler Verarbeitung

Herrmann, M. J., Würflein, H., Schreppel, T., Koehler, S., Mühlberger, A., Reif, A., Canli, T., Romanos, M., Jacob, C. P., Lesch, K.-P. and Fallgatter, A. J. (2009). Catechol-O-methyltransferase val158met genotype affects neural correlates of aversive stimuli processing. Cognitive, Affective, and Behavioral Neurociences, 159, 1032-1043.

Herrmann, M. J. , Schreppel, T., Biehl, S.C., Jacob, C., Heine, M., Boreatti-Hümmer, A., Mühlberger, A. , Fallgatter, A. J. (2009) Emotional deficits in adult ADHD patients: an ERP study. Social Cognitive and Affective Neuroscience, 4: 340-345

 

2. Klinische Fragestellungen

2.a Alters und Demenzforschung

Koordinator: Julia Zeller

Herrmann, M. J., Langer, J. B., Jacob, C., Ehlis, A. C., & Fallgatter, A. J. (2008). Reduced prefrontal oxygenation in Alzheimer disease during verbal fluency tasks. Am J Geriatr Psychiatry, 16(2), 125-135.

Zeller, J. B., Herrmann, M. J., Ehlis, A. C., Polak, T. & Fallgatter, A. J. (2010). Altered parietal brain oxygenation in Alzheimer's disease as assessed with Near-Infrared Spectroscopy Am J Geriatr Psychiatry,  18: 433-441

2.b Angsterkrankungen

Koordinator: Thomas Dresler

Dresler, T., Ehlis, A. C., Plichta, M. M., Richter, M. M., Jabs, B., Lesch, K. P. and  Fallgatter, A. J. (2009) Panic disorder and a possible treatment approach by means of high-frequency rTMS: a case report. World J Biol Psychiatry, 10, 991-997.

2.c ADHS

Koordinator: Stefanie Biehl
Fragestellung: Verbesserung der präfrontalen Hirnaktierung durch medikamentöse Therapie mit Methylphenidat in Abhängigkeit von der genetischen Ausstattung

Herrmann, M. J., Saathoff, C., Schreppel, T. J., A.-C., E., Scheuerpflug, P., P., P., & A.J., F. (2009). The effect of ADHD symptoms on performance monitoring in a non-clinical population. Psychiatry  Research, 169, 144-148

Koehler, S., Lauer, P., Schreppel, T., Jacob, C., Heine, M., Boreatti-Hummer, A., Fallgatter, A. J., & Herrmann, M. J. (2009). Increased EEG power density in alpha and theta bands in adult ADHD patients. J Neural Transm, 116(1), 97-104.

Herrmann, M.J., Pfahler, K., Huter, T., Jacob, C., Heine, M., Boreatti-Hümmer, A., Ehlis, A.-C., Scheuerpflug, P., Lesch, K.-P., Fallgatter, A.J. (2010) Neural correlates of performance monitoring in adult patients with Attention Deficit Hyperactivity Disorder (ADHD)  World Journal of Biological Psychiatry, 11, 457-64.

3. Neurophysiologische Methoden

3.a NIRS

Koordinator: Thomas Dresler

Herrmann, M. J., Woidich, E., Schreppel, T., Pauli, P., & Fallgatter, A. J. (2008). Brain activation for alertness measured with functional near infrared spectroscopy (fNIRS). Psychophysiology, 45(3), 480-486.

Dresler, T., Obersteiner, A., Schecklmann, M. et al. (2009) Arithmetic tasks in different formats and their influence on behavior and brain oxygenation as assessed with near-infrared spectroscopy (NIRS): a study involving primary and secondary school children. J Neural Transm, 116, 1689-1700.

3.b fMRI

Koordinator: Hahn
Hahn, T., Dresler, T., Ehlis, A. C. et al. (2009) Neural response to reward anticipation is modulated by Gray's impulsivity. Neuroimage, 46, 1148-1153.

Hahn, T., Dresler, T., Plichta, M. M. et al. Functional Amygdala-Hippocampus Connectivity During Anticipation of Aversive Events is Associated with Gray's Trait Sensitivity to Punishment. Biol Psychiatry.

3.c EEG

Koordinator: Biehl

3.d tdcs

Koordinator: Manish Asthana

3.d Startle

Koordinator: Agnes Gajewska

3.e TMS und Neuronavigation

Koordinator: Sara Tupak